Histone H3 (acetyl K14) Recombinant Rabbit Monoclonal Antibody [JU43-26]

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

H3K14ac antibody

Abbreviation

HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ,H3K14ac

Swiss Prot

P68431 Human, P68433 Mouse, Q6LED0 Rat

Cellular Locus

Nucleus. Chromosome.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human Histone H3 aa 1-50 / 136 (acetyl K14) .

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP, SNAP-ChIP, CUT&Tag-seq

Positive Control

Jurkat cell lysate, rat liver tissue lysate, mouse lung tissue lysate, Hela whole cell lysate, Hela treated with 1μM TSA for 18 hours whole cell lysate, F9, Hela, MCF-7, PC-3M, rat brain tissue, human kidney tissue, rat hippocampus tissue, human colon tissue, mouse testis tissue.