PXR Ligand 2
Product Specifications
UNSPSC Description
PXR Ligand 2 (Compound 55) is the target protein ligand for PROTAC SMARCA2/4-degrader-34 (HY-169279)[1].
Target Antigen
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pxr-ligand-2.html
Smiles
O=C(C1=CC=C(C(NC(C2=C(N(N=N2)C3=CC(OC)=C(C=C3OC)OCC4=CC=CC=C4)C)=O)=C1)O[C@@H](CC)CCC)OC
Molecular Weight
602.68
References & Citations
[1]Huber A D, et al. First-in-Class Small Molecule Degrader of Pregnane X Receptor Enhances Chemotherapy Efficacy[J]. Journal of Medicinal Chemistry, 2024.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169280/PXR-Ligand-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169280/
Clinical Information
No Development Reported
Curated Selection
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