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Histone H1.2 Recombinant Rabbit Monoclonal Antibody [JU43-48]

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

H1 histone family member 2 antibody H1.a antibody H12_HUMAN antibody H1F2 antibody H1s-1 antibody HIST1H1C antibody Histone 1 H1c antibody Histone cluster 1 H1c antibody Histone H1.2 antibody Histone H1c antibody Histone H1d antibody Histone H1s-1 antibody MGC3992 antibody

Abbreviation

HIST1H1C, H1F2

Swiss Prot

P16403 Human, P15864 Mouse, P15865 Rat

Cellular Locus

Nucleus. Chromosome.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human Histone H12 aa 1-50 / 213.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, ChIP

Positive Control

Hela cell lysate, 293 cell lysate, MCF-7 cell lysate, rat liver tissue lysate, mouse lung tissue lysate, Hela, PC-3M, SK-Br-3, mouse colon tissue, human kidney tissue, rat brain tissue, human lung carcinoma tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:100 ;IF-Tissue: 1:50-1:100 ;IHC-P: 1:50-1:200 ;ChIP: Use 0.5~2 μg for 25 μg of chromatin.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

21 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

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