Galectin 1 Recombinant Rabbit Monoclonal Antibody [JM13-37]

Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Specifically, Galectin-1 is an autocrine regulator of cell-proliferation that plays a role in the maintenance of G0 and in the control of G2 traverse. Galectin-1, also known as LGALS1, is the protein product of a single gene linked to human chromosome 22q13.1. The Galectin-1 protein contains 135 amino acids, a single internal EcoRI site and a polyadenylation signal. Galectin-1 can localize to both intracellular and extracellular space. Galectin-1 is expressed in human placenta, human lung, HL-6, HepG2 and CEM cells.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

14 kDa laminin-binding protein antibody 14 kDa lectin antibody Beta galactoside binding lectin antibody Beta galactoside binding lectin L 14 I antibody beta galactoside binding protein antibody Beta-galactoside-binding lectin L-14-I antibody DKFZp686E23103 antibody Gal 1 antibody Gal-1 antibody GAL1 antibody Galaptin antibody Galbp antibody Galectin antibody Galectin-1 antibody Galectin1 antibody GBP antibody HBL antibody HLBP14 antibody HPL antibody L 14.5 antibody L-14.5 antibody L14 antibody Lactose binding lectin 1 antibody Lactose-binding lectin 1 antibody Lect14 antibody Lectin galactoside binding soluble 1 antibody Lectin galactoside-binding soluble 1 antibody LEG1_HUMAN antibody LGALS 1 antibody LGALS1 antibody Lgals1 lectin galactose binding soluble 1 antibody MAPK activating protein MP12 antibody Putative MAPK activating protein MP12 antibody Putative MAPK-activating protein PM12 antibody S Lac lectin 1 antibody S-Lac lectin 1 antibody

Abbreviation

Gal-1, HLBP14, LGALS1

Swiss Prot

P09382 Human, P16045 Mouse, P11762 Rat

Cellular Locus

Cytoplasm, Extracellular matrix, Secreted.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human Galectin 1 aa 1-50 / 135.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP, FC

Positive Control

HL-60 cell lysate, A549 cell lysate, HCT 116 cell lysate, NIH/3T3 cell lysate, L6 cell lysate, mouse kidney tissue lysate, mouse colon tissue lysate, NIH/3T3, L6, rat stomach tissue, human placenta tissue.