DDAH1 Recombinant Rabbit Monoclonal Antibody [JM53-18]
DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
DDAH-1, Dimethylarginine dimethylaminohydrolase 1, DDAH1, DDAH
Swiss Prot
O94760 Human
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human DDAH1 aa 100-285 / 285.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IP
Positive Control
Human kidney tissue lysate, human liver tissue lysate, human prostate tissue, human kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000-1:5,000 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 31 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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