mtTFA Recombinant Rabbit Monoclonal Antibody [JM32-44]

Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

anscription factor 6-like 1 antibody Mitochondrial transcription factor 1 antibody mitochondrial transcription factor A antibody MtTF1 antibody mtTFA antibody TCF 6 antibody TCF-6 antibody TCF6 antibody TCF6L1 antibody TCF6L2 antibody TCF6L3 antibody TFAM antibody TFAM_HUMAN antibody Transcription factor 6 antibody Transcription factor 6 like 2 (mitochondrial transcription factor) antibody Transcription factor 6 like 2 antibody Transcription factor 6-like 2 antibody transcription factor 6-like 3 antibody Transcription factor A, mitochondrial antibody Transcription factor A, mitochondrial antibody Transcription factor A, mitochondrial precursor antibody

Abbreviation

mtTFA, MtTF1, TCF-6, TFAM, TCF6, TCF6L2

Swiss Prot

Q00059 Human

Cellular Locus

Mitochondrion, Mitochondrion matrix, mitochondrion nucleoid.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human mtTFA aa 41-90 / 246.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP

Positive Control

K-562 cell lysate, HL-60 cell lysate, HeLa cell lysate, HepG2 cell lysate, MCF7 cell lysate, Human brain tissue lysate, human kidney tissue, human colon tissue, HeLa, human colon cancer tissue.