RRM2 Recombinant Rabbit Monoclonal Antibody [JM93-43]
Belongs to the ribonucleoside diphosphate reductase small chain family. Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.it have two regulatory sites: the specificity site, which controls substrate specificity, and the activity site which regulates overall catalytic activity. A substrate-binding catalytic site, located on M1, is formed only in the presence of the second subunit M2.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
RRM2, RR2
Swiss Prot
P31350 Human
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human RRM2 aa 1-147 / 389.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IP, IF-Cell, IF-Tissue, IHC-P
Positive Control
Hela cell lysates, HepG2 cell lysate, human tonsil tissue, human appendix tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:20-1:50 ;IF-Tissue: 1:20-1:50 ;IP: 1:10-1:50 ;IHC-P: 1:200-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 45 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Human IgG Immunoglobulin (IG266), CF640R conjugate, 0.1mg/mL
PAX5 / BSAP (Early B-Cell Marker) (PCRP-PAX5-1B1), CF640R conjugate, 0.1mg/mL
MAGE A1 (MZ2E/838), CF594 conjugate, 0.1mg/mL
