WDR5 Recombinant Rabbit Monoclonal Antibody [JM73-53]

Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

2410008O07Rik antibody AA408785 antibody AA960360 antibody BIG 3 antibody Big antibody BIG3 antibody BMP2 induced 3 kb gene protein antibody BMP2 induced gene, 3-KB antibody BMP2-induced 3-kb gene protein antibody MGC114572 antibody OTTHUMP00000162494 antibody SWD 3 antibody SWD3 antibody SWD3 Set1c WD40 repeat protein homolog antibody WD repeat containing protein 5 antibody WD repeat domain 5 antibody WD repeat protein 5 antibody WD repeat-containing protein 5 antibody WD repeat-containing protein BIG-3 antibody WDR 5 antibody Wdr5 antibody WDR5_HUMAN antibody

Abbreviation

WDR5, BIG3

Swiss Prot

P61964 Human, P61965 Mouse, Q498M4 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human WDR5 aa 285-334 / 334.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

HeLa cell lysate, Saos-2 cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, PC-12 cell lysate, Mouse spleen tissue lysate, Rat spleen tissue lysate, human breast carcinoma tissue, human colon carcinoma tissue, human thyroid tissue, mouse brain tissue, rat brain tissue, PC-12.