Carcino Embryonic Antigen CEA Recombinant Rabbit Monoclonal Antibody [JM93-28]

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster of Differentiation 66e), is a member of the carcinoembryonic antigen (CEA) gene family. In the literature, CEACAM5 is often used as a synonym for cancer embryonic antigen (CEA), a well-known biomarker of many types of malignancies, colorectal cancer in the first place. Its primary function in the embryonic intestine and colon tumors is adhesion between epithelial cells. Also, it plays a significant role in the inhibition of differentiation and apoptosis in colon cells. There are evidences that high CEACAM5 expression is firmly associated with the CD133-positive colorectal cancer stem cells.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Carcinoembryonic antigen antibody Carcinoembryonic antigen-related cell adhesion molecule 5 antibody CD66e antibody CEA antibody Ceacam5 antibody CEAM5_HUMAN antibody DKFZp781M2392 antibody Meconium antigen 100 antibody OTTHUMP00000199032 antibody OTTHUMP00000199033 antibody OTTHUMP00000199034 antibody

Abbreviation

CEA, CD66e, CEACAM5

Swiss Prot

P06731 Human

Cellular Locus

Membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Human Carcinoembryonic Antigen (CEA) purified from human liver.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P

Positive Control

A549 cell lysate, MCF7 cell lysate, BxPC-3 cell lysate, HUVEC, MCF-7, human lung cancer tissue, human stomach carcinoma tissue, human colon carcinoma tissue.