Monoclonal CtIP Antibody

<strong>Monoclonal CtIP Antibody</strong>_x000D_ <strong>Catalog number:</strong> B2016966_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 µL_x000D_ <strong>Molecular Weight or Concentration:</strong> 120 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20¬∞C_x000D_ <strong>Keywords:</strong> RBBP8, RIM, COM1, JWDS, SAE2, SCKL2_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wang XS, Zhao J, Wu-Baer F, Shao Z, Lee BJ, Cupo OM, Rabadan R, Gautier J, Baer R, Zha S. CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25700-25711._x000D_ 2: Rozier L, Guo Y, Peterson S, Sato M, Baer R, Gautier J, Mao Y. The MRN-CtIP pathway is required for metaphase chromosome alignment Mol Cell. 2013 Mar 28;49(6):1097-107._x000D_ 3: Wang J, Ding Q, Fujimori H, Motegi A, Miki Y, Masutani M. Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors Oncotarget. 2016 Feb 16;7(7):7701-14._x000D_ 4: Salles D, Mencalha AL, Ireno IC, Wiesm√ºller L, Abdelhay E. BCR-ABL stimulates mutagenic homologous DNA double-strand break repair via the DNA-end-processing factor CtIP Carcinogenesis. 2011 Jan;32(1):27-34._x000D_ 5: Yu X, Baer R. Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor J Biol Chem. 2000 Jun 16;275(24):18541-9._x000D_ 6: Wu-Baer F, Baer R. Effect of DNA damage on a BRCA1 complex Nature. 2001 Nov 1;414(6859):36._x000D_ 7: Bothmer A, Rommel PC, Gazumyan A, Polato F, Reczek CR, Muellenbeck MF, Schaetzlein S, Edelmann W, Chen PL, Brosh RM Jr, Casellas R, Ludwig T, Baer R, Nussenzweig A, Nussenzweig MC, Robbiani DF. Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching J Exp Med. 2013 Jan 14;210(1):115-23._x000D_ 8: Sun X, Bai J, Xu J, Xi X, Gu M, Zhu C, Xue H, Chen C, Dong J. Multiple DSB Resection Activities Redundantly Promote Alternative End Joining-Mediated Class Switch Recombination Front Cell Dev Biol. 2021 Nov 26;9:767624._x000D_ 9: Dong S, Han J, Chen H, Liu T, Huen MSY, Yang Y, Guo C, Huang J. The human SRCAP chromatin remodeling complex promotes DNA-end resection Curr Biol. 2014 Sep 22;24(18):2097-2110._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25404348">10: Xu J, Husain A, Hu W, Honjo T, Kobayashi M. APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17242-7. </a>_x000D_ _x000D_ <strong>Products Related to Monoclonal CtIP Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>