NFAT2 Recombinant Rabbit Monoclonal Antibody [JA81-03]
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
NF-ATc1, NFATc1, NF-ATc, NFATc, NFATC1, NFAT2, NFATC
Swiss Prot
O95644 Human
Cellular Locus
Cytoplasm. Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human NFAT2 aa 894-943 / 943.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
K-562 cell lysates, human tonsil tissue, K-562.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 101 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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