delta Sarcoglycan Recombinant Rabbit Monoclonal Antibody [JM61-10]
Selected Variant
ET1703-88
Size: 100 µL
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder. Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
Delta-SG, 35DAG, SGCD
Swiss Prot
Q92629 Human
Cellular Locus
Cytoskeleton, sarcolemma.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human delta Sarcoglycan aa 221-265 / 289.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IP, IHC-P
Positive Control
Human lung tissue lysate, human skeletal muscle tissue lysate, human stomach carcinoma tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
32 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
Price
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