NMDAR1 Recombinant Rabbit Monoclonal Antibody [JM11-26]

Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+.Sensitivity to glutamate and channel kinetics depend on the subunit composition.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

GluN1 antibody Glutamate [NMDA] receptor subunit zeta-1 antibody Glutamate receptor ionotropic N methyl D aspartate 1 antibody Glutamate receptor ionotropic, N-methyl-D aspartate, subunit 1 antibody glutamate receptor ionotropic, NMDA 1 antibody Grin1 antibody MRD8 antibody N methyl D aspartate receptor antibody N methyl D aspartate receptor channel subunit zeta 1 antibody N methyl D aspartate receptor subunit NR1 antibody N-methyl-D-aspartate receptor subunit NR1 antibody NMD-R1 antibody NMDA 1 antibody NMDA R1 antibody NMDA receptor 1 antibody NMDA1 antibody NMDAR antibody NMDZ1_HUMAN antibody NR1 antibody

Abbreviation

GluN1, NMD-R1

Swiss Prot

Q05586 Human, P35438 Mouse, P35439 Rat

Cellular Locus

Cell membrane, postsynaptic cell membrane, postsynaptic density.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within human NMDAR1 aa 870-910.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC, IHC-Fr

Positive Control

MCF7 cell lysate, human brain tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, N2A, SHG-44, SH-SY5Y, mouse cerebral cortex tissue, rat cerebral cortex tissue, mouse hippocampus tissue, mouse cerebral cortex tissue, rat cerebral cortex tissue.