Podoplanin Recombinant Rabbit Monoclonal Antibody [JM31-21]

Puromycin aminonucleoside nephrosis (PAN) is a rat model for human minimal change nephropathy. During PAN, severe proteinuria is induced that is paralleled by a reduced expression of a rat podocyte protein, named podoplanin. Podoplanin, also known as glycoprotein 38 (gp38) is a type I membrane protein. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Aggrus antibody Glycoprotein 36 KD antibody Glycoprotein 36 antibody gp 36 antibody GP 38 antibody GP 40 antibody gp36 antibody GP38 antibody GP40 antibody HT1A 1 antibody HT1A1 antibody hT1alpha 1 antibody hT1alpha 2 antibody hT1alpha1 antibody hT1alpha2 antibody Lung type I cell membrane associated glycoprotein antibody Lung type I cell membrane associated glycoprotein isoform a antibody Lung type I cell membrane associated glycoprotein T1A 2 antibody OTS 8 antibody OTS8 antibody OTTHUMP00000009640 antibody OTTHUMP00000044504 antibody PA2.26 antibody PA2.26 antigen antibody Pdpn antibody PDPN_HUMAN antibody Podoplanin antibody PSEC0003 antibody PSEC0025 antibody T1 alpha antibody T1 ALPHA GENE antibody T1-alpha antibody T1A 2 antibody T1A antibody TI1A antibody TIA 2 antibody TIA2 antibody

Abbreviation

Gp36, T1A

Swiss Prot

Q86YL7 Human

Cellular Locus

Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human Podoplanin aa 35-75 / 162.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

Human lung tissue lysates, human lung tissue, human breast tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;IHC-P: 1:50-1:400

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 17 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

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