CYP2E1 Recombinant Rabbit Monoclonal Antibody [JM10-85]

A cytochrome P450 monooxygenase involved in the metabolism of fatty acids . Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) .Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics (Probable).

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

4-nitrophenol 2-hydroxylase antibody CP2E1_HUMAN antibody CPE1 antibody CYP2E antibody Cyp2e1 antibody CYPIIE1 antibody Cytochrome P450 2E1 antibody Cytochrome P450 isozyme 3A antibody Cytochrome P450 LM3A antibody Cytochrome P450, family 2, subfamily e, polypeptide 1 antibody cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 antibody Cytochrome P450, subfamily IIE antibody Cytochrome P450-ALC antibody Cytochrome P450-J antibody Cytochrome P450RLM6 antibody EC 1.14.13.- antibody EC 1.14.13.n7 antibody Ethanol-inducible P450 antibody Flavoprotein-linked monooxygenase antibody MGC133529 antibody Microsomal monooxygenase antibody OTTHUMP00000020813 antibody OTTHUMP00000046571 antibody P450 ALC antibody P450-J antibody P450C2E antibody P450J antibody P450RLM6 antibody Xenobiotic monooxygenase antibody

Abbreviation

Cytochrome P450 2E1, CYP2E1, CYP2E

Swiss Prot

P05181 Human, Q05421 Mouse, P05182 Rat

Cellular Locus

Endoplasmic reticulum, Membrane, Microsome, Mitochondrion, Mitochondrion inner membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human CYP2E1 aa 71-114 / 439.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Tissue, IHC-P

Positive Control

Human liver tissue lysates, Mouse liver tissue lysate, Rat liver tissue lysate, human liver tissue, mouse liver tissue, rat liver tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:5,000 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 57 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

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