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Glucagon Recombinant Rabbit Monoclonal Antibody [JF33-10]

Glucagon is a pancreatic hormone that functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. Glucagon-like peptide-1 (GLP-1), Glucagon-like peptide-2 (GLP-2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the Glucagon family of hormones. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior, whereas GLP-2 is a stimulator of intestinal epithelial growth. VIP causes vasodilation resulting in the lowering of blood pressure. PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones, including growth hormone.

Product Specifications

Product Name Alternative

GCG antibody glicentin-related polypeptide antibody GLP-1 antibody GLP-1 (7-36) antibody GLP-1 (7-37) antibody GLP-2 antibody GLP1 antibody GLP1, included antibody GLP2 antibody GLP2, included antibody GLUC_HUMAN antibody Glucagon antibody Glucagon like peptide 1 antibody glucagon-like peptide 1 antibody Glucagon-like peptide 1, included antibody Glucagon-like peptide 2 antibody Glucagon-like peptide 2, included antibody GRPP antibody OXM antibody OXY antibody preproglucagon antibody

Abbreviation

GCG

Swiss Prot

P01275 Human

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human GLP1 aa 65-150.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P

Positive Control

PC-12, SW480, human pancreas tissue.

Concentration

1 mg/mL

Dilution

WB: 1;500-1:1,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

21/8/4 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

CAS Number

9000-83-3

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