TGN46 Recombinant Rabbit Monoclonal Antibody [JF1-024]
TGN38 (trans-Golgi network protein 2) is a type I integral membrane protein that constitutively cycles between the TGN and plasma membrane where it partitions nascent proteins into carrier vesicles for transport to appropriate destinations in the cell. The cytosolic domain of TGN38 interacts with AP2 Clathrin adaptor complexes via the tyrosine-containing motif (SDYQRL) to direct internalization from the plasma membrane. N- and O-linked oligosaccharide chains attach to the core TGN38 protein to produce a protein present in brain, lung and kidney.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
TGOLN2
Swiss Prot
O43493 Human, Q62314 Mouse
Cellular Locus
Cell membrane, Golgi apparatus.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within Human TGN46 aa 43-79 / 437L5L562:L576.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IP, IF-Cell, FC
Positive Control
NIH/3T3 cell lysate, Hela cell lysate, human kidney tissue, human liver tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IP: 1:50-1:100 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:100 ;FC: 1:1000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
95 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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