Fas (CD95) Recombinant Rabbit Monoclonal Antibody [JJ0942]
The Fas receptor, also known as Fas, FasR, apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6), is a protein that in humans is encoded by the FAS gene.Fas was first identified using a monoclonal antibody generated by immunizing mice with the FS-7 cell line. Thus, the name Fas is derived from FS-7-associated surface antigen.The Fas receptor is a death receptor on the surface of cells that leads to programmed cell death (apoptosis) if it binds its ligand, Fas ligand (FasL). It is one of two apoptosis pathways, the other being the mitochondrial pathway.[8]
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
FAS
Swiss Prot
P25445 Human
Cellular Locus
Cell membrane, Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human Fas aa 130-335 / 335.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Tissue, IHC-P
Positive Control
A431 cell lysate, Hela cell lysate, human tonsil tissue, human kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 37 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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