CXCL12/SDF1 Recombinant Rabbit Monoclonal Antibody [JJ09-20]

The stromal cell derived factor 1 (SDF1, CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1 isoforms (SDF1α and SDF1β) that have different properties and biological activities. Additional isoforms of SDF1 have been reported.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

12-O-tetradecanoylphorbol 13-acetate repressed protein 1 antibody AI174028 antibody C-X-C motif chemokine 12 antibody Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) antibody Chemokine (C-X-C motif) ligand 12 antibody Chemokine CXC motif ligand 12 antibody cxcl12 antibody hIRH antibody hSDF-1 antibody Intercrine reduced in hepatomas antibody IRH antibody OTTHUMP00000019491 antibody PBSF antibody Pre-B cell growth-stimulating factor antibody SCYB12 antibody SDF 1 antibody SDF-1 antibody SDF-1-alpha (3-67) antibody SDF-1a antibody SDF-1b antibody SDF1_HUMAN antibody SDF1A antibody SDF1B antibody Stromal cell-derived factor 1 antibody Stromal cell-derived factor 1 delta antibody Stromal cell-derived factor 1 gamma antibody Stromal cell-derived factor 1a antibody Stromal cell-derived factor-1 alpha antibody Thymic lymphoma cell-stimulating factor antibody Tlsf antibody TLSF-a antibody TLSF-b antibody Tlsfa antibody Tlsfb antibody TPAR1 antibody

Abbreviation

SDF-1, hSDF-1, IRH, hIRH, PBSF, CXCL12

Swiss Prot

P48061 Human

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant full length protein of human SDF1.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P

Positive Control

Human kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:200 ;IHC-P: 1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 11 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

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