ARID1A Recombinant Rabbit Monoclonal Antibody [JJ09-01]
The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2α) and Brg-1 (also designated SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID 1A) and BAF250b (ARID1B), are thought to play regulatory roles.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
ARID domain-containing protein 1A, BAF250, BAF250A, hOSA1, ARID1A
Swiss Prot
O14497 Human, A2BH40 Mouse
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human ARID1A aa 1,184-1,334 / 2,285.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Cell, IF-Tissue, IHC-P
Positive Control
SH-SY5Y, Hela, 293, human spleen tissue, mouse testis tissue, mouse colon tissue, mouse kidney tissue, rat testis tissue.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:400
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 242 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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