Cdc37 Recombinant Rabbit Monoclonal Antibody [JJ087-06]
Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK, as well as eIF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CDC37
Swiss Prot
Q16543 Human, Q61081 Mouse, Q63692 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human Cdc37 aa 1-50 / 378.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC, IP
Positive Control
A431 cell lysate, K562 cell lysate, mouse liver tissue, mouse placenta tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000 ;FC: 1:50-1:100 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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