Hsp22 Recombinant Rabbit Monoclonal Antibody [JJ08-53]
Heat shock protein beta-8 is a protein that in humans is encoded by the HSPB8 gene. Mutations in this gene have been associated with an autosomal dominant rimmed vacuolar myopathy The clinical features of this condition are distal and proximal myopathy. MRI show severe relatively symmetric multifocal fatty degenerative changes within the muscles. Muscle biopsy shows rimmed vacuoles, muscle fiber atrophy and endomysial fibrosis.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
HspB8
Swiss Prot
Q9UJY1 Human, Q9JK92 Mouse, Q9EPX0 Rat
Cellular Locus
Nucleus, Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human Hsp22 aa 1-50 / 196.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P
Positive Control
HepG2 cell lysate, mouse skeletal muscle tissue lysate, Hela, A431, SH-SY5Y, mouse brain tissue, rat skeletal muscle tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 22 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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