Cdc34 Recombinant Rabbit Monoclonal Antibody [JJ086-07]
CDC34 is a gene that in humans encodes the protein Ubiquitin-conjugating enzyme E2 R1. This protein is a member of the ubiquitin-conjugating enzyme family, which catalyzes the covalent attachment of ubiquitin to other proteins. CDC34 was originally discovered by work in baker's yeast as a gene that is essential for the cell cycle. Cdc34 in yeast targets numerous substrates - notably the cyclin-dependent kinase inhibitor Sic1 for ubiquitin-mediated protein degradation. CDC34 is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication.
Product Specifications
Product Name Alternative
Abbreviation
CDC34
Swiss Prot
P49427 Human, Q8CFI2 Mouse
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human Cdc34 aa 1-236 / 236.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, FC, IP
Positive Control
293 cell lysate, K562 cell lysate, Hela, A549, N2A, Jurkat.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000;FC: 1:50-1:100;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 27 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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