Cdc34 Recombinant Rabbit Monoclonal Antibody [JJ086-07]
Selected Variant
ET1701-10
Size: 100 µL
CDC34 is a gene that in humans encodes the protein Ubiquitin-conjugating enzyme E2 R1. This protein is a member of the ubiquitin-conjugating enzyme family, which catalyzes the covalent attachment of ubiquitin to other proteins. CDC34 was originally discovered by work in baker's yeast as a gene that is essential for the cell cycle. Cdc34 in yeast targets numerous substrates - notably the cyclin-dependent kinase inhibitor Sic1 for ubiquitin-mediated protein degradation. CDC34 is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CDC34
Swiss Prot
P49427 Human, Q8CFI2 Mouse
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Cdc34 aa 1-236 / 236.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, FC, IP
Positive Control
293 cell lysate, K562 cell lysate, Hela, A549, N2A, Jurkat.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000;FC: 1:50-1:100;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 27 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
Price
Frequently Asked Questions
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