14-3-3 Theta Recombinant Rabbit Monoclonal Antibody [SD084-02]
14-3-3 protein theta is a protein that in humans is encoded by the YWHAQ gene. This gene product belongs to the 14-3-3 family of proteins that mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence that is polymorphic; however, there is no correlation between the repeat number and the disease.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
YWHAQ
Swiss Prot
P27348 Human, P68254 Mouse, P68255 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human 14-3-3 Theta aa 1-50 / 245.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, FC
Positive Control
MCF-7 cell lysate, Hela cell lysate, Hela, A431, A549, SH-SY5Y.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:5,000;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 28 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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