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14-3-3 Theta Recombinant Rabbit Monoclonal Antibody [SD084-02]

14-3-3 protein theta is a protein that in humans is encoded by the YWHAQ gene. This gene product belongs to the 14-3-3 family of proteins that mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence that is polymorphic; however, there is no correlation between the repeat number and the disease.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

14-3-3 antibody 14-3-3 protein T-cell antibody 14-3-3 protein tau antibody 14-3-3 protein theta antibody 1C5 antibody HS1 antibody theta polypeptide antibody tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein antibody tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta isoform antibody tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide antibody

Abbreviation

YWHAQ

Swiss Prot

P27348 Human, P68254 Mouse, P68255 Rat

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human 14-3-3 Theta aa 1-50 / 245.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, FC

Positive Control

MCF-7 cell lysate, Hela cell lysate, Hela, A431, A549, SH-SY5Y.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:5,000;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 28 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

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