Cyclin E2 Recombinant Rabbit Monoclonal Antibody [SD2035]
Cyclin E2 is a protein that in humans is encoded by the CCNE2 gene. It is a G1 cyclin that binds Cdk2 and is inhibited by p27 (Kip1) and p21 (Cip1). It plays a role in the G1/S portion of the cell cycle and also has putative interactions with proteins CDKN1A, CDKN1B, and CDK3. Aberrant expression can lead to cancer.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CCNE2
Swiss Prot
O96020 Human, Q7TMS8 Mouse, Q9Z238 Mouse
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within C-terminal human Cyclin E2.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
NIH/3T3, Hela, MCF-7, human breast carcinoma tissue.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:50-1:500;IF-Tissue: 1:50-1:500;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
47 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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