HNF-4-alpha Recombinant Rabbit Monoclonal Antibody [SN72-03]

HNF-4 alpha is a transcription factor that binds DNA as a homodimer. HNF-4 alpha is important in liver, kidney, and intestinal development. It has also been intensely studied as one of a variety of genes responsible for diabetes mellitus. HNF-4 alpha has been shown in knock out mice to be essential for the morphogenic and functional differentiation of hepatocytes. HNF-4 alpha is a dominant regulator of epithelial phenotypes able to drive the mesenchymal-to-epithelial transition when expressed in fibroblasts.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

FLJ39654 antibody FRTS4 antibody Hepatic nuclear factor 4 alpha antibody Hepatocyte nuclear factor 4 alpha antibody Hepatocyte nuclear factor 4 antibody Hepatocyte nuclear factor 4-alpha antibody HNF 4 alpha antibody HNF 4 antibody HNF-4-alpha antibody HNF4 antibody HNF4A antibody HNF4A_HUMAN antibody HNF4a7 antibody HNF4a8 antibody HNF4a9 antibody Hnf4alpha antibody HNF4alpha10/11/12 antibody MODY 1 antibody MODY antibody MODY1 antibody NR2A1 antibody NR2A21 antibody Nuclear receptor subfamily 2 group A member 1 antibody OTTHUMP00000031060 antibody OTTHUMP00000031062 antibody TCF 14 antibody TCF antibody TCF-14 antibody TCF14 antibody Tcf4 antibody Transcription factor 14, hepatic nuclear factor antibody Transcription factor 14 antibody Transcription factor HNF 4 antibody Transcription factor HNF-4 antibody Transcription factor HNF4 antibody

Abbreviation

HNF-4-alpha, TCF-14, HNF4A

Swiss Prot

P41235 Human, P49698 Mouse, P22449 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human HNF-4-alpha aa 21-70 / 474.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

A549 cell lysates, LOVO cell lysates, HepG2, SW480, human colon cancer tissue, human small intestine tissue, mouse colon tissue, rat colon tissue, Mouse liver tissue lysate, Mouse kidney tissue lysate, Mouse brain tissue lysate.