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AKAP14 Recombinant Rabbit Monoclonal Antibody [SC0667]

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Binds to type II regulatory subunits of protein kinase A and anchors/targets them.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

A kinase (PRKA) anchor protein 14 antibody A kinase anchor protein 14 antibody A kinase anchor protein 28 kDa antibody A-kinase anchoring protein 28 antibody AKAP14 antibody AKAP28 antibody PRKA14 antibody Protein kinase A anchoring protein 14 antibody

Abbreviation

AKAP-14, AKAP 28, PRKA14, AKAP14

Swiss Prot

Q86UN6 Human

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human AKAP14 aa 135-170 / 197.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IP

Positive Control

HUVEC, Jurkat, Hela, A549.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:5,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

23 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

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