PIM1 Recombinant Rabbit Monoclonal Antibody [ST0513]

Pim-1 is a serine/threonine kinase that cooperates with c-Myc in lymphoid cell transformation. The expression of pim-1 increases during the progression from early to late G1, remaining high at the G1/S boundary and G2 phases of the cell cycle. Pim-1 is regulated at both the transcriptional and translational level, and it has been shown to be induced by IL-2 stimulation. Pim-1 also plays a role in T cell differentiation, and it has been shown to stimulate c-Myc-mediated apoptosis upstream of caspase-3-like proteases.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Oncogene PIM 1 antibody Oncogene PIM1 antibody PIM 1 antibody pim 1 kinase 44 kDa isoform antibody Pim 1 kinase antibody pim 1 oncogene (proviral integration site 1) antibody Pim 1 oncogene antibody PIM antibody PIM1 antibody pim1 kinase 44 kDa isoform antibody PIM1_HUMAN antibody Pim2 antibody PIM3 antibody Proto oncogene serine/threonine protein kinase Pim 1 antibody Proto-oncogene serine/threonine-protein kinase Pim-1 antibody Proviral integration site 1 antibody Proviral integration site 2 antibody

Abbreviation

PIM1

Swiss Prot

P11309 Human, P06803 Mouse

Cellular Locus

Cytoplasm, Nucleus, Cell membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within human PIM1 aa 20-60.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P

Positive Control

K-562 cell lysate, TF-1 cell lysate, 22RV1 cell lysate, K-562, BT-20, HepG2, SW480, human tonsil tissue, human colon carcinoma tissue, human spleen tissue, human breast carcinoma tissue, human breast tissue.