beta II Tubulin Recombinant Rabbit Monoclonal Antibody [ST52-04]
Tubulin is a major cytoskeleton component that has five distinct forms, designated a, b, g, d and e tubulin. a and b tubulins form heterodimers which multimerize to form a microtubule filament. Multiple b Tubulin isoforms (b1, b2, b3, b4, b5, b6 and b8) have been characterized and are expressed in mammalian tissues. b1 and b4 are present throughout the cytosol, b2 is present in the nuclei and nucleoplasm, and b3 is a neuron-specific cytoskeletal protein. g Tubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both d Tubulin and e Tubulin are associated with the centrosome. d Tubulin is a homolog of the Chlamydomonas d Tubulin Uni3 and is found in association with the centrioles, whereas e Tubulin localizes to the pericentriolar material. e Tubulin exhibits a cell cycle-specific pattern of localization; first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
TUBB2B, TUBB2A, TUBB2, TUBB4B, TUBB2C
Swiss Prot
P68371 Human, Q13885 Human, Q9BVA1 Human, P68372 Mouse, Q7TMM9 Mouse, Q9CWF2 Mouse, P85108 Rat, Q3KRE8 Rat, Q6P9T8 Rat
Cellular Locus
Cytoplasm, Cytoskeleton, Microtubule.
Host
Rabbit
Species Reactivity
Mouse,Rat,Human
Immunogen
Synthetic peptide within Human beta Ⅱ Tubulin aa 407-445 / 445.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, IP
Positive Control
Mouse brain tissue lysate, mouse kidney tissue lysate, N2A, mouse kidney tissue, mouse brain tissue, rat brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 50 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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