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AMPK alpha 1 Recombinant Rabbit Monoclonal Antibody [SU03-48]

5'-AMP-activated protein kinase catalytic subunit alpha-1 is an enzyme that in humans is encoded by the PRKAA1 gene. The protein encoded by this gene belongs to the serine/threonine protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

5 AMP activated protein kinase alpha 1catalytic subunit antibody 5 AMP activated protein kinase catalytic alpha 1 chain antibody 5' AMP activated protein kinase catalytic subunit alpha 1 antibody 5'-AMP-activated protein kinase catalytic subunit alpha-1 antibody AAPK1 antibody AAPK1_HUMAN antibody ACACA kinase antibody acetyl CoA carboxylase kinase antibody AI194361 antibody AI450832 antibody AL024255 antibody AMP -activate kinase alpha 1 subunit antibody AMP-activated protein kinase, catalytic, alpha -1 antibody AMPK 1 antibody AMPK alpha 1 antibody AMPK alpha 1 chain antibody AMPK antibody AMPK subunit alpha-1 antibody AMPK1 antibody AMPKa1 antibody AMPKalpha1 antibody C130083N04Rik antibody cb116 antibody EC 2.7.11.1 antibody HMG CoA reductase kinase antibody HMGCR kinase antibody hormone sensitive lipase kinase antibody Hydroxymethylglutaryl CoA reductase kinase antibody im:7154392 antibody kinase AMPK alpha1 antibody MGC33776 antibody MGC57364 antibody OTTHUMP00000161795 antibody OTTHUMP00000161796 antibody PRKAA 1 antibody PRKAA1 antibody Protein kinase AMP activated alpha 1 catalytic subunit antibody SNF1-like protein AMPK antibody SNF1A antibody Tau protein kinase PRKAA1 antibody wu:fa94c10 antibody

Abbreviation

AMPK subunit alpha-1, ACACA kinase, HMGCR kinase, PRKAA1, AMPK1

Swiss Prot

Q13131 Human, Q5EG47 Mouse, P54645 Rat

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human AMPK alpha aa 501-550 / 559.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, FC, IP, IHC-Fr, IHC-P

Positive Control

HeLa cell lysate, MCF7 cell lysate, K-562 cell lysate, 293T cell lysate, HT-29 cell lysate, L-929 cell lysate, C6 cell lysate, HeLa, L-929, human lung cancer tissue, mouse hippocampus tissue, mouse cerebral cortex tissue.

Concentration

1 mg/mL

Dilution

WB: 1:5,000 ;IF-Cell: 1:100-1:250 ;IF-Tissue: 1:50-1:200 ;FC: 1:1,000 ;IP: Use at an assay dependent concentration. ;IHC-Fr: 1:100 ;IHC-P: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 64 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

Curated Selection

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