B Raf Recombinant Rabbit Monoclonal Antibody [SU34-04]
BRAF is a human gene that encodes a protein called B-Raf. The gene is also referred to as proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene homolog B, while the protein is more formally known as serine/threonine-protein kinase B-Raf. The B-Raf protein is involved in sending signals inside cells which are involved in directing cell growth. In 2002, it was shown to be mutated in some human cancers. Certain other inherited BRAF mutations cause birth defects.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
BRAF
Swiss Prot
P15056 Human, P28028 Mouse,
Cellular Locus
Nucleus, Cytoplasm, Cell membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within human B Raf aa 60-100.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC, IP
Positive Control
Rat brain tissue, human placenta tissue, human pancreas tissue, mouse fallopian tube tissue, mouse brain tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 84 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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