Bak Recombinant Rabbit Monoclonal Antibody [SU32-07]
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
Bcl2-L-7, BAK1, BAK, BCL2L7, CDN1
Swiss Prot
Q16611 Human
Cellular Locus
Mitochondrion membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human Bak aa 1-50 / 211.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Tissue, IHC-P, IP
Positive Control
HeLa cell lysate, AGS cell lysate, HEK-293 cell lysate, human colon tissue, human stomach carcinoma tissue, human small intestine tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:500-1:1,000 ;IP: 1-2μg/sample
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 23 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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