Cdk5 Recombinant Rabbit Monoclonal Antibody [SR39-01]
Cyclin dependent kinase 5 is a protein, and more specifically an enzyme, that is encoded by the Cdk5 gene. It was discovered 15 years ago and it is saliently expressed in post-mitotic central nervous system neurons (CNS). The molecule belongs to the cyclin-dependent kinase family. Kinases are enzymes that catalyze reactions of phosphorylation, a process that allows the substrate to gain a phosphate group donated by an organic compound known as ATP. Phosphorylations are of vital importance during glycolysis, therefore, making kinases an essential part of the cell due to their role in the metabolism, cell signaling and many other processes.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
TPKII catalytic subunit
Swiss Prot
Q00535 Human, P49615 Mouse, Q03114 Rat
Cellular Locus
Cytoplasm, Nucleus, Cell membrane, Perikaryon, Cell junction
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human Cdk5 aa 243-292 / 292.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC, IP
Positive Control
Hela cell lysate, SH-SY5Y cell lysate, MCF-7 cell lysate, rat brain tissue, mouse brain tissue, human thyroid carcinoma tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P:1:50-1:400 ;FC: 1:50 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 33 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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