Bad Recombinant Rabbit Monoclonal Antibody [SA32-01]
The BCL2 associated agonist of cell death (BAD) protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis. BAD is a member of the BH3-only family, a subfamily of the Bcl-2 family. It does not contain a C-terminal transmembrane domain for outer mitochondrial membrane and nuclear envelope targeting, unlike most other members of the Bcl-2 family. After activation, it is able to form a heterodimer with anti-apoptotic proteins and prevent them from stopping apoptosis.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
BAD, Bcl2-L-8
Swiss Prot
Q92934 Human, Q61337 Mouse, O35147 Rat
Cellular Locus
Cytoplasm, Mitochondrion outer membrane
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human Bad aa 1-50 / 168.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Positive Control
MCF-7 cell lysates, Hela, MCF-7, human skin tissue, human breast carcinoma tissue, human kidney tissue, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:50;IF-Tissue: 1:50;IHC-P: 1:50-1:200;FC: 1:50;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 18 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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