MuERVL-Gag Rabbit Polyclonal Antibody
A large number of retrotransposons are expressed when the zygotic genome is first transcribed, including the endogenous retroviruses (ERVs), LINE-1 elements, and the non-autonomous SINE elements. At the 2C stage, MuERV-L/MERVL retrovirus-like elements are transiently de-repressed and produce 3% of the transcribed mRNAs. Following the 2C stage, MERVL-retroelement expression is silenced. The newly study discovered that this regulated pattern of MERVL expression overlapped with greater than one hundred 2C-specific genes that have co-opted regulatory elements from these foreign retroviruses to initiate their transcription.
Product Specifications
CAS Number
9007-83-4
Abbreviation
Gag
Swiss Prot
V9H130 Mouse
Host
Rabbit
Species Reactivity
Mouse
Immunogen
Synthetic peptide within mouse MuERVL-Gag aa 541-581/581.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell, WB
Positive Control
Mouse embryo, ES-D3 cell lysate, ES-W4 cell lysate.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:200 ;WB: 1:1,000-1:5,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 67 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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