Chromogranin A Rabbit Polyclonal Antibody
Chromogranin A is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). Chromogranin A might promote the generation of secretory granules. It is used as an indicator for pancreas and prostate cancer. It might play a role in early neoplasic progression. It is also elevated in diabetes.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
CgA
Swiss Prot
P10645 Human, P26339 Mouse, P10354 Rat
Cellular Locus
Cytoplasmic vesicle, secreted.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide corresponding to C-terminal of Mouse Chromogranin A aa 408-457 / 457 (ID: P10645).
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC, IF-Tissue, IF-Cell
Positive Control
PC12 cell lysate, human pancreas tissue, mouse pancreas tissue, rat pancreas tissue, human colon cancer tissue, Lovo.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:200-1:1,000 ;FC: 1:100-1:200 ;IF-Tissue: 1:200 ;IF-Cell: 1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 52 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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