FYCO1 Rabbit Polyclonal Antibody
This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2).
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
FYCO1
Swiss Prot
Q9BQS8 Human, Q8VDC1 Mouse
Cellular Locus
Lysosome, Endosome, autophagosome.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human FYCO1 aa 1-200.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
SK-Br-3 cell lysates, rat testis tissue, human liver tissue, human thyroid tissue, human colon tissue, mouse colon tissue, 293.
Concentration
1 mg/mL
Dilution
WB:1:500 ;IHC-P:1:200-1:1,000 ;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
167 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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