ZAC Rabbit Polyclonal Antibody
Zinc-activated ion channel (ZAC), is a human protein encoded by the ZACN gene. ZAC forms a cation-permeable ligand-gated ion channel of the "Cys-loop" superfamily. The ZAC gene is present in humans and dogs, but no ortholog is thought to exist in the rat or mouse genomes. ZAC mRNA is expressed in prostate, thyroid, trachea, lung, brain (adult and fetal), spinal cord, skeletal muscle, heart, placenta, pancreas, liver, kidney and stomach. The endogenous ligand for ZAC is thought to be Zn2+, although ZAC has also been found to activate spontaneously. The function of spontaneous ZAC activation is unknown.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Zinc-activated ligand-gated ion channel Ligand-gated ion channel zinc-activated 1 Ligand-gated ion-channel receptor L2 L2 LGICZ LGICZ1 ZAC
Abbreviation
ZACN
Swiss Prot
Q401N2 Human
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human ZAC aa 139-188 / 412.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Human kidney tissue lysate, HepG2 cell lysate, N2A, SiHa, rat brain tissue, human liver tissue, human kidney tissue.
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000;IF-Cell:1:50-1:100;IHC-P:1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 46 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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