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STIM2 Rabbit Polyclonal Antibody

Plays a role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. Functions as a highly sensitive Ca2+ sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca2+-influx. Regulates basal cytosolic and endoplasmic reticulum Ca2+ concentrations. Upon mild variations of the endoplasmic reticulum Ca2+ concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca2+ release-activated Ca2+ (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca2+ influx.

Product Specifications

Product Name Alternative

FLJ39527 antibody KIAA1482 antibody STIM 2 antibody STIM2 antibody STIM2_HUMAN antibody Stromal interaction molecule 2 antibody

Abbreviation

STIM2, KIAA1482

Swiss Prot

Q9P246 Human, P83093 Mouse

Cellular Locus

Endoplasmic reticulum.

Host

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Recombinant protein within Human STIM2 aa 1-140 / 746.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

293T, AGS, Hela, human kidney tissue, human placenta tissue, mouse testis tissue.

Concentration

1 mg/mL

Dilution

WB:1:500-1:1,000;IF-Cell:1:50-1:200;IHC-P:1:50-1:200

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 84 kDa.

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

CAS Number

9007-83-4

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