STIM2 Rabbit Polyclonal Antibody
Plays a role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. Functions as a highly sensitive Ca2+ sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca2+-influx. Regulates basal cytosolic and endoplasmic reticulum Ca2+ concentrations. Upon mild variations of the endoplasmic reticulum Ca2+ concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca2+ release-activated Ca2+ (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca2+ influx.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
FLJ39527 antibody KIAA1482 antibody STIM 2 antibody STIM2 antibody STIM2_HUMAN antibody Stromal interaction molecule 2 antibody
Abbreviation
STIM2, KIAA1482
Swiss Prot
Q9P246 Human, P83093 Mouse
Cellular Locus
Endoplasmic reticulum.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within Human STIM2 aa 1-140 / 746.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
293T, AGS, Hela, human kidney tissue, human placenta tissue, mouse testis tissue.
Concentration
1 mg/mL
Dilution
WB:1:500-1:1,000;IF-Cell:1:50-1:200;IHC-P:1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 84 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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