ATP2A1/SERCA1 Rabbit Polyclonal Antibody
Key regulator of striated muscle performance by acting as the major Ca2+ ATPase responsible for the reuptake of cytosolic Ca2+ into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
SERCA1, SR Ca (2+)-ATPase 1, ATP2A1
Swiss Prot
O14983 Human, Q8R429 Mouse, Q64578 Rat
Cellular Locus
Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetis peptide within mouse ATP2A1 aa 1-50 / 994.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Human skeletal muscle tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue, 293T.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 110 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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