NaV1.7 Rabbit Polyclonal Antibody

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na (+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na (+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

ETHA antibody GEFSP7 antibody hNE Na antibody hNE-Na antibody hNENa antibody NE NA antibody NENA antibody Neuroendocrine sodium channel antibody Peripheral sodium channel 1 antibody PN1 antibody Scn9a antibody SCN9A_HUMAN antibody Sodium channel protein type 9 subunit alpha antibody Sodium channel protein type IX subunit alpha antibody Sodium channel voltage gated type IX alpha antibody Sodium channel voltage gated type IX alpha polypeptide antibody Sodium channel voltage gated type IX alpha subunit antibody Voltage gated sodium channel alpha subunit Nav1.7 antibody Voltage gated sodium channel subunit alpha Nav1 antibody Voltage-gated sodium channel subunit alpha Nav1.7 antibody

Abbreviation

hNE-Na, PN1, SCN9A, NENA

Swiss Prot

Q15858 Human, O08562 Rat

Cellular Locus

Plasma membrane. In neurite terminals.

Host

Rabbit

Species Reactivity

Human,Rat

Immunogen

Synthetic peptide within Human NaV17 aa 1,939-1,988 / 1,988.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

IF-Cell, IHC-P

Positive Control

SH-SY5Y, A549, Hela, human placenta tissue, rat testis tissue, mouse colon tissue, human liver tissue.

Concentration

1 mg/mL

Dilution

IF-Cell: 1:50-1:200;IHC-P: 1:50-1:600

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 226 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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