IL-6R, Rat (HEK293, Fc)

IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway[1][2]. with a fibronectin type-III-like domain contained in the N-terminal part and a transmembrane domain. Soluble IL-6R (sIL-6R) interacts with SORL1 to conduct internalization and binds IL-6 and dimerized gp130 to deliver trans signalin. IL-6R alpha, Rat is soluble form and produced in HEK293 cells with a C-Terminal hFc-tag.

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