NaV1.7 Rabbit Polyclonal Antibody
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na+ channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
hNE-Na, PN1, SCN9A, NENA
Swiss Prot
Q15858 Human
Cellular Locus
Cell membrane. Cell projection.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human NaV17 aa 1-50 / 1,988.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell, IHC-P, FC
Positive Control
A549, Hela, HepG2, SH-SY5Y, human liver cancer tissue, mouse colon tissue.
Concentration
1 mg/mL
Dilution
IHC-P: 1:50-1:1,000;IF-Cell: 1:50-1:500;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 226 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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