ZIP12 Rabbit Polyclonal Antibody
Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia. On the basis of sequence homology, the human SLC39A12 gene has been included as a member of a family of zinc (Zn) transporters designated as the ZRT-IRT-like proteins (current designation SLC39). ZRT-IRT-like proteins act in concert with another family of transporters, known in non-mammalian organisms as cation diffusion facilitators and in mammals as zinc transporters (ZnT), to regulate the distribution of Zn in the extra- versus intracellular milieu and within cellular compartments. Hence the ZnT maintain Zn homeostasis that is critical for the normal functioning of tissues including the CNS.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
LZT-Hs8, ZIP-12, SLC39A12, ZIP12
Swiss Prot
Q504Y0 Human, Q5FWH7 Mouse
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human ZIP12 aa 685-691 / 691 (Extracellular).
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
HepG2, N2A, SH-SY5Y, rat lung tissue, mouse liver tissue, mouse brain tissue, mouse eyeball tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 70 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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