Caveolin-1 Mouse Monoclonal Antibody [19-D6]
Caveolin, an integral membrane protein, is a principal component of caveolae membranes in vivo. Two isoforms of caveolin have been identified: a slower migrating 24-kDa species (-isoform) and a faster migrating 21-kDa species (-isoform). Caveolins interact with multiple signaling molecules, such as the G-protein alpha subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases and eNOS. Caveolin-1 has been implicated in the pathogenesis of mammary epithelial cell hyperplasia.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
CAV1
Swiss Prot
Q03135 Human, P49817 Mouse, P41350 Rat
Cellular Locus
Cell membrane, Golgi apparatus membrane.
Host
Mouse
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Mouse Caveolin-1 aa 129-178 / 178.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
A431 cell lysates, NIH/3T3 cell lysates, L929, rat lung tissue, human lung tissue, mouse lung tissue, mouse liver tissue, mouse bladder tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500;IHC-P: 1:200;IF-Cell: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 20 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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