CD55 Mouse Monoclonal Antibody [12F1]
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade . Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage .
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
CD55,Complement decay-accelerating factor
Swiss Prot
P08174 Human
Cellular Locus
Cell membrane, Membrane, Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human CD55 aa 150- 381.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, FC
Positive Control
Hela, SW1990.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:1,000 ;FC: 1:50-1:100
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 41 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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