MUC1 Mouse Monoclonal Antibody [A4D9]
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
MUC1
Swiss Prot
P15941 Human
Cellular Locus
Apical cell membrane. Secreted. Nucleus, Cell membrane, Cytoplasm.
Host
Mouse
Species Reactivity
Human
Immunogen
Synthetic peptide of core peptide domain of human MUC1.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
IHC-P, FC, IF-Cell
Positive Control
Human breast tissue, human kidney tissue, human uterus tissue, human colon carcinoma tissue, human breast carcinoma tissue, MCF-7, HeLa.
Concentration
2 mg/mL
Dilution
IHC-P: 1:50-1:500 ;FC: 1:50-1:100 ;IF-Cell: 1:500
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size 122 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![BRCA1 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1C4]](https://cdn.genprice.uk/products/937/68dd1b78061270361ea1b26a/imageurl/ta802672bm.webp)
BRCA1 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1C4]
PI 4 Kinase type 2 beta (PI4K2B) (NM_018323) Human Over-expression Lysate
