CASK Mouse Monoclonal Antibody [A1C7]
Peripheral plasma membrane protein CASK is a protein that in humans is encoded by the CASK gene. This gene is also known by several other names: CMG 2 (CAMGUK protein 2), calcium/calmodulin-dependent serine protein kinase 3 and membrane-associated guanylate kinase 2.Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Peripheral plasma membrane protein CASK ,hCASK,Calcium/calmodulin-dependent serine protein kinase,Protein lin-2 homolog,CASK
Swiss Prot
O14936 Human, O70589 Mouse, Q62915 Rat
Cellular Locus
Cell membrane, Cytoplasm, Membrane, Nucleus.
Host
Mouse
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human CASK aa 311-513 / 926.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Siha cell lysate, A549 cell lysate, rat large intestine tissue, human prostate cancer tissue, mouse brain tissue, SW620.
Concentration
2 mg/mL
Dilution
WB:1:500-1:1000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 105 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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